The Bully Wee travel to Stirling tomorrow, for a meeting of the bottom two sides in the IRN-BRU Third Division meet at Forthbank Stadium.
For Clyde, David Marsh, Gavin Brown and Michael Oliver are all ruled out, with John Sweeney and Stef McCluskey also doubtful.
However, on loan Kevin Nicoll is expected to return.
“We took a heavy defeat from East Stirling in midweek as we did not take the chances we had when the game was goalless,” Jim Duffy said.
“We had good openings and in games as tight as the ones in the Third Division are you have to be more ruthless than we were. Hopefully we can do that tomorrow and get the points.”